Remote Ischemic Conditioning in Traumatic Brain Injury

Abstract

Traumatic Brain Injury (TBI) is a major cause of disability, with no effective treatments for repetitive mild TBI (RmTBI). Remote Ischemic Conditioning (RIC) shows promise in stroke and may aid RmTBI recovery by reducing neuroinflammation. Using a mouse model, we found RIC significantly improved motor function post-RmTBI (p < 0.05), though anxiety and cognition remained unaffected. Ongoing studies will explore RIC’s effects on neuroinflammation and sex-based differences, highlighting its potential for clinical translation in RmTBI treatment.