Resist the Randomized Controlled Trials fetish: different questions require different pyramids of evidence

Authors

  • Raywat Deonandan University of Ottawa

DOI:

https://doi.org/10.36834/cmej.80355

References

1. Greenhalgh T, MacIntyre CR, Baker MG, et al. Masks and respirators for prevention of respiratory infections: a state of the science review. Clin Microbiol Rev. 2024;37(2):e00124-23. https://doi.org/10.1128/cmr.00124-23

2. Jefferson T, Dooley L, Ferroni E, et al. Physical interventions to interrupt or reduce the spread of respiratory viruses. Cochrane Database Syst Rev. 2023;1(1):Cd006207. https://doi.org/10.1002/14651858.CD006207.pub6

3. Yeh RW, Valsdottir LR, Yeh MW, et al. Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial. BMJ. 2018;363:k5094. https://doi.org/10.1136/bmj.k5094

4. Austin PC. An Introduction to propensity score methods for reducing the effects of confounding in observational studies. Multivariate Behav Res. 2011;46(3):399-424. https://doi.org/10.1080/00273171.2011.568786

5. Cheurfa C, Tsokani S, Kontouli K-M, Boutron I, Chaimani A. Synthesis methods used to combine observational studies and randomised trials in published meta-analyses. Syst Rev. 2024;13(1):70. https://doi.org/10.1186/s13643-024-02464-w

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Published

2025-02-24

How to Cite

1.
Deonandan R. Resist the Randomized Controlled Trials fetish: different questions require different pyramids of evidence. Can. Med. Ed. J [Internet]. 2025 Feb. 24 [cited 2025 Mar. 9];16(1):126-7. Available from: https://journalhosting.ucalgary.ca/index.php/cmej/article/view/80355

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Commentary and Opinions

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